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Journal of Nanomaterials
Volume 2015, Article ID 705390, 6 pages
Review Article

Rare Earth Doped Apatite Nanomaterials for Biological Application

1Biomedical Materials and Engineering Center, Wuhan University of Technology, Wuhan 430070, China
2Faculty of Applied Sciences, Sabaragamuwa University of Sri Lanka, 70140 Belihuloya, Sri Lanka
3State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, 122 Luoshi Road, Wuhan 430070, China

Received 3 July 2014; Accepted 2 October 2014

Academic Editor: Daniela Predoi

Copyright © 2015 Thalagalage Shalika Harshani Perera et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In most biological analyses, a sensitive detection technique is primarily dependent on the fluorescence labeling agent. New generation of fluorophores called rare earth doped apatite nanoparticle (REAnp) has the ability to emit near infrared radiations which are of low absorptivity by tissue chromophores and especially suitable for biological system imaging. Moreover, bioapatite is demonstrated to be an excellent candidate for biomedical applications because of its biocompatibility, biodegradability, and bioactivity. During recent years a lot of efforts have been made for achievement of REAnp for medical diagnostics and targeted therapeutics applications. In this review, we discuss the significance of REAnps in biological systems, different root of synthesis, and biological applications. Also we discuss the future studies for the effective biological applications of REAnps.