Gold Nanoparticles Increase PLK1-Specific Small Interfering RNA Transfection and Induce Apoptosis of Drug Resistance Breast Cancer Cells

Figure 2

(a) Gel retardation assay of GNPs-siRNA. Lanes from left to right indicate different weight ratios (4, 2, 1, 0.5, and 0.125) between GNPs and siRNA. The 0 weight ratio stands for free siRNA. (b) TEM images of GNPs. Scale bars: 20 nm. (c) UV-VIS spectra of GNPs, GNPs-PEI, and GNPs-siRNA from 450 to 700 nm. (d) Zeta potential of GNPs, GNPs-PEI, and GNPs-siRNA. (e) Diameters of GNPs, GNPs-PEI, and GNPs-siRNA. (f) X-ray images and intensity ratios of GNPs-PEI with different weights (1: 35 μg, 2: 70 μg, 3: 140 μg, and 4: 280 μg).

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