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Journal of Nanomaterials
Volume 2015, Article ID 721251, 7 pages
Research Article

SWCNT-Based Biosensor Modelling for pH Detection

1Faculty of Electrical Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia
2Department of Electrical Engineering, Islamic Azad University, Yasooj Branch, Yasooj, Iran
3Department of Electrical Engineering, Urmia University, Urmia, Iran

Received 16 October 2014; Accepted 5 January 2015

Academic Editor: Stefan I. Voicu

Copyright © 2015 Mohammad Javad Kiani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Different forms of CNT delivery have been discovered with several biomedical functions during past decades. The mechanisms of the cellular uptake of CNTs are mainly maintained due to the chemical nature, the cell type, and the features of the molecules, which are used to functionalize the nanotube exterior. Since single-wall carbon Nanotube (SWCNT) has unique chemical and physical properties, it is a great applicant for pH sensing. In addition, ion sensitive FET (ISFET) base on nanostructured SWCNT have covered a new method to help genetic investigators restructure metabolic pathways in cells, recognize the progression of disease, and expand diagnostics and therapeutics. Particularly, because PH sensing is very crucial for the constancy of enzymes, it is essential to extend the cost efficient types of this sensing. In this research, the conductance changes of the CNT-based ISFET device with different pH values can be modelled by ion concentration of the solution. In addition, the electrical current of channel is imagined as a function of pH levels, which can be controlled by a control factor (). Thus, ISFET based nanostructured SWCNT is proposed focusing on the area of electrical detection of hydrogen ions of the electrolyte membrane. Besides, electrical detection of hydrogen ion applications is suggested to be used by modelling the delivery of SWCNT sheets. In the end, after comparing the proposed model and experimental data, it has been reported that there is a good compatibility between them.