Efficient Synthesis of Single-Chain Polymer Nanoparticles via Amide Formation

Figure 2

Synthesis route to SCNPs via intrachain amide formation at high dilution (OCN–R–CNO = bifunctional isocyanate compound; DBN = 1,5-diazabicyclo[4.3.0]non-5-ene; THF = tetrahydrofuran).