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Journal of Nanomaterials
Volume 2015, Article ID 756278, 11 pages
Review Article

Recent Research Trends and Future Prospects in Nanozymes

1Department of BioNano Technology, Gachon University, 1342 Seongnamdae-ro, Sujeong-gu, Seongnam, Gyeonggi 461-701, Republic of Korea
2Department of Chemistry, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul 156-756, Republic of Korea

Received 21 July 2015; Accepted 17 November 2015

Academic Editor: Xuping Sun

Copyright © 2015 Ho Yun Shin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Recently, nanomaterial-based enzyme mimetics (nanozymes) have attracted enormous interest. They exhibit unique advantages such as excellent robustness, stability, and low-cost production with easy scale-up, which are critically needed as an alternative to natural enzymes. These nanozymes exhibit natural enzyme-like activity and have been applied to various kinds of detection and treatment methods for biomolecules such as DNA, proteins, cells, and small molecules including glucose. To highlight progress in the field of nanozymes, this review discusses recent nanozyme-based research results and their applications for the development of novel biosensor, immunoassay, cancer diagnostics, therapeutics, and environmental engineering technologies. Current challenges and future prospects of nanozymes for widespread use in biotechnology are also discussed.