Research Article
Preparation of Cefquinome Nanoparticles by Using the Supercritical Antisolvent Process
Table 2
Analysis of L9(34) test results.
| | Run | (A) Concentration of solution (mg/mL) | (B) Cefquinome solution feeding speed (mL/min) | (C) Precipitation pressure (Mpa) | (D) Precipitation temperature (°C) | Average diameter (m) |
| | 1 | 1 | 1 | 1 | 1 | 0.92 | | 2 | 1 | 2 | 2 | 2 | 0.72 | | 3 | 1 | 3 | 3 | 3 | 0.88 | | 4 | 2 | 1 | 2 | 3 | 1.11 | | 5 | 2 | 2 | 3 | 1 | 1.05 | | 6 | 2 | 3 | 1 | 2 | 0.91 | | 7 | 3 | 1 | 3 | 2 | 2.06 | | 8 | 3 | 2 | 1 | 3 | 1.12 | | 9 | 3 | 3 | 2 | 1 | 0.96 | | 0.84 | 1.363 | 0.983 | 0.977 | | | 1.023 | 0.963 | 0.93 | 1.23 | | | 1.38 | 0.917 | 1.33 | 1.037 | | | 0.54 | 0.446 | 0.4 | 0.253 | | | Optimal level | A1 | B3 | C2 | D1 | |
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= (mean particle size at )/3, the mean values of mean particle size for a certain factor at each level with standard deviation.
= .
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