Fluorescent Gold Nanoclusters: Synthesis and Recent Biological Application

Figure 14

Fluorescent images showed the cell apoptosis induced by (a) AuNCs alone; (b) AuNCs-Her; (c) Herceptin by staining the nucleus with Hoechst 33258 (UV light 460 nm). FLIM shows the DNA damage of SK-BR3 cells induced by (d) AuNCs-Her; (e) Herceptin indicated by the bright yellow dots. (f) Quantitative evaluation of DNA damage of cells as a percentage of the total number of cells for different treatments. Reprinted with permission from [177], ©2011, American Chemical Society.