Fluorescent Gold Nanoclusters: Synthesis and Recent Biological Application

Figure 16

Schematic illustration of in situ biosynthesis of gold nanoclusters in cells and tumor imaging (top). Representative xenograft tumor mouse models of hepatocellular carcinoma observed in normal light (a) or by in vivo fluorescence imaging (b) 24 h after a subcutaneous injection of 10 mmol/L HAuCl₄ solution near the tumor; (c) 24 h after a subcutaneous injection of 10 mmol/L HAuCl₄ solution near the tumor. (d) Control mouse observed by in vivo fluorescence imaging 48 h after a subcutaneous injection of 10 mmol/L HAuCl₄ solution in the right side of their abdomen (bottom). Reprinted from the permission of [181], Copyright ©2013, Rights Managed by Nature Publishing Group.