Table of Contents Author Guidelines Submit a Manuscript
Journal of Nanomaterials
Volume 2015, Article ID 913254, 7 pages
http://dx.doi.org/10.1155/2015/913254
Research Article

Preparation and Characterization of Paclitaxel Loaded SF/PLLA-PEG-PLLA Nanoparticles via Solution-Enhanced Dispersion by Supercritical CO2

Zheng Zhao,1,2,3 Yi Li,2 and Yu Zhang4

1State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China
2Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Kowloon, Hong Kong
3Biomedical Materials and Engineering Research Center of Hubei Province, Wuhan University of Technology, Wuhan 430070, China
4Department of Mechanical Engineering, The Hong Kong Polytechnic University, Kowloon, Hong Kong

Received 10 March 2015; Revised 31 May 2015; Accepted 17 June 2015

Academic Editor: Mircea Chipara

Copyright © 2015 Zheng Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H.-Y. Cho, C. K. Lee, and Y.-B. Lee, “Preparation and evaluation of PEGylated and folate-PEGylated liposomes containing paclitaxel for lymphatic delivery,” Journal of Nanomaterials, vol. 2015, Article ID 471283, 10 pages, 2015. View at Publisher · View at Google Scholar · View at Scopus
  2. F. Danhier, P. Danhier, C. J. De Saedeleer et al., “Paclitaxel-loaded micelles enhance transvascular permeability and retention of nanomedicines in tumors,” International Journal of Pharmaceutics, vol. 479, no. 2, pp. 399–407, 2015. View at Publisher · View at Google Scholar · View at Scopus
  3. G. Ruan and S.-S. Feng, “Preparation and characterization of poly(lactic acid)-poly(ethylene glycol)-poly(lactic acid) (PLA-PEG-PLA) microspheres for controlled release of paclitaxel,” Biomaterials, vol. 24, no. 27, pp. 5037–5044, 2003. View at Publisher · View at Google Scholar · View at Scopus
  4. F. Danhier, N. Lecouturier, B. Vroman et al., “Paclitaxel-loaded PEGylated PLGA-based nanoparticles: in vitro and in vivo evaluation,” Journal of Controlled Release, vol. 133, no. 1, pp. 11–17, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. P.-P. Lv, W. Wei, H. Yue, T.-Y. Yang, L.-Y. Wang, and G.-H. Ma, “Porous quaternized chitosan nanoparticles containing paclitaxel nanocrystals improved therapeutic efficacy in non-small-cell lung cancer after oral administration,” Biomacromolecules, vol. 12, no. 12, pp. 4230–4239, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. A. K. Singla, A. Garg, and D. Aggarwal, “Paclitaxel and its formulations,” International Journal of Pharmaceutics, vol. 235, no. 1-2, pp. 179–192, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. T. Yang, M.-K. Choi, F.-D. Cui et al., “Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposome,” Journal of Controlled Release, vol. 120, no. 3, pp. 169–177, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. R. T. Liggins and H. M. Burt, “Paclitaxel-loaded poly (L-lactic acid) microspheres 3: blending low and high molecular weight polymers to control morphology and drug release,” International Journal of Pharmaceutics, vol. 282, no. 1-2, pp. 61–71, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. Z. Zhang and S.-S. Feng, “The drug encapsulation efficiency, in vitro drug release, cellular uptake and cytotoxicity of paclitaxel-loaded poly(lactide)-tocopheryl polyethylene glycol succinate nanoparticles,” Biomaterials, vol. 27, no. 21, pp. 4025–4033, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. K. M. Huh, H. S. Min, S. C. Lee, H. J. Lee, S. Kim, and K. Park, “A new hydrotropic block copolymer micelle system for aqueous solubilization of paclitaxel,” Journal of Controlled Release, vol. 126, no. 2, pp. 122–129, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. B. Patil, U. S. Toti, A. Khdair, L. Ma, and J. Panyam, “Single-step surface functionalization of polymeric nanoparticles for targeted drug delivery,” Biomaterials, vol. 30, no. 5, pp. 859–866, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. Z. Keresztessy, M. Bodnár, E. Ber et al., “Self-assembling chitosan/poly-γ-glutamic acid nanoparticles for targeted drug delivery,” Colloid and Polymer Science, vol. 287, no. 7, pp. 759–765, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. L. Brannon-Peppas and J. O. Blanchette, “Nanoparticle and targeted systems for cancer therapy,” Advanced Drug Delivery Reviews, vol. 56, no. 11, pp. 1649–1659, 2004. View at Publisher · View at Google Scholar · View at Scopus
  14. Y. Lian, J.-C. Zhan, K.-H. Zhang, and X.-M. Mo, “Fabrication and characterization of curcumin-loaded silk fibroin/P(LLA-CL) nanofibrous scaffold,” Frontiers of Materials Science, vol. 8, no. 4, pp. 354–362, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. B.-J. Dong and Q. Lu, “Conductive Au nanowires regulated by silk fibroin nanofibers,” Frontiers of Materials Science, vol. 8, no. 1, pp. 102–105, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. Z. Zhao, Y. Li, and M. Xie, “Silk fibroin-based nanoparticles for drug delivery,” International Journal of Molecular Sciences, vol. 16, no. 3, pp. 4880–4903, 2015. View at Publisher · View at Google Scholar
  17. M. Chen, Z. Shao, and X. Chen, “Paclitaxel-loaded silk fibroin nanospheres,” Journal of Biomedical Materials Research, Part A, vol. 100, no. 1, pp. 203–210, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. P. Wu, Q. Liu, R. Li et al., “Facile preparation of paclitaxel loaded silk fibroin nanoparticles for enhanced antitumor efficacy by locoregional drug delivery,” ACS Applied Materials and Interfaces, vol. 5, no. 23, pp. 12638–12645, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. T. Deepak, D. Michel, and P. Yashwant, Nanoparticulate Drug Delivery Systems, Informa Healthcare USA, New York, NY, USA, 2007.
  20. B. Dhurai, N. Saraswathy, R. Maheswaran et al., “Electrospinning of curcumin loaded chitosan/poly (lactic acid) nanofilm and evaluation of its medicinal characteristics,” Frontiers of Materials Science, vol. 7, no. 4, pp. 350–361, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. C. G. Mothé, A. D. Azevedo, W. S. Drumond, S. H. Wang, and R. D. Sinisterra, “Preparation and characterization of poly(l,l-lactide)-b-poly(ethylene glycol)-b-poly(l,l-lactide) (PLLA-PEG-PLLA) microspheres having encapsulated tetracycline,” Journal of Thermal Analysis and Calorimetry, vol. 106, no. 3, pp. 671–677, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. A.-Z. Chen, L. Li, S.-B. Wang et al., “Study of Fe3O4-PLLA-PEG-PLLA magnetic microspheres based on supercritical CO2: preparation, physicochemical characterization, and drug loading investigation,” The Journal of Supercritical Fluids, vol. 67, pp. 139–148, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. Z. Zhao, Y. Li, Y. Zhang et al., “Development of silk fibroin modified poly(L-lactide)-poly(ethylene glycol)-poly(L-lactide) nanoparticles in supercritical CO2,” Powder Technology, vol. 268, no. 1, pp. 118–125, 2014. View at Publisher · View at Google Scholar · View at Scopus
  24. A.-Z. Chen, L. Li, S.-B. Wang et al., “Nanonization of methotrexate by solution-enhanced dispersion by supercritical CO2,” Journal of Supercritical Fluids, vol. 67, pp. 7–13, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. Z. Zhao, A. Z. Chen, Y. Li et al., “Fabrication of silk fibroin nanoparticles for controlled drug delivery,” Journal of Nanoparticle Research, vol. 14, no. 4, article 736, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. Z. Zhao, Y. Li, A.-Z. Chen et al., “Generation of silk fibroin nanoparticles via solution-enhanced dispersion by supercritical CO2,” Industrial & Engineering Chemistry Research, vol. 52, no. 10, pp. 3752–3761, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. Y. Kang, J. Wu, G. Yin et al., “Characterization and biological evaluation of paclitaxel-loaded poly(L-lactic acid) microparticles prepared by supercritical CO2,” Langmuir, vol. 24, no. 14, pp. 7432–7441, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. L. Y. Lee, C. H. Wang, and K. A. Smith, “Supercritical antisolvent production of biodegradable micro- and nanoparticles for controlled delivery of paclitaxel,” Journal of Controlled Release, vol. 125, no. 2, pp. 96–106, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. W. Li, G. Liu, L. Li, J. Wu, Y. Lü, and Y. Jiang, “Effect of process parameters on co-precipitation of paclitaxel and poly(L-lactic acid) by supercritical antisolvent process,” Chinese Journal of Chemical Engineering, vol. 20, no. 4, pp. 803–813, 2012. View at Publisher · View at Google Scholar · View at Scopus
  30. P. Ouyang, Y.-Q. Kang, G.-F. Yin, Z.-B. Huang, Y.-D. Yao, and X.-M. Liao, “Fabrication of hydrophilic paclitaxel-loaded PLA-PEG-PLA microparticles via SEDS process,” Frontiers of Materials Science in China, vol. 3, no. 1, pp. 15–24, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. J. Liu, Y. Huang, A. Kumar et al., “PH-sensitive nano-systems for drug delivery in cancer therapy,” Biotechnology Advances, vol. 32, no. 4, pp. 693–710, 2014. View at Publisher · View at Google Scholar · View at Scopus
  32. S. J. T. Rezaei, H. S. Abandansari, M. R. Nabid, and H. Niknejad, “PH-responsive unimolecular micelles self-assembled from amphiphilic hyperbranched block copolymer for efficient intracellular release of poorly water-soluble anticancer drugs,” Journal of Colloid and Interface Science, vol. 425, pp. 27–35, 2014. View at Publisher · View at Google Scholar · View at Scopus