Effects of End-Terminal Capping on Transthyretin (105–115) Amyloid Protofibrils Using Steered Molecular Dynamics

Figure 2

A constraint for the tensile simulations, computed by SMD simulation. The blue boxed region of TTR amyloid protofibril was fixed. The red boxed area, corresponding to the top two layers of the protofibril, was pulled along the fibril axis, which is parallel to -axis.