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Journal of Nanomaterials
Volume 2016, Article ID 5760327, 9 pages
Research Article

Electrochemiluminescence Biosensor Based on Thioglycolic Acid-Capped CdSe QDs for Sensing Glucose

1Department of Chemistry, Hannam University, Daejeon 305-811, Republic of Korea
2Division of Radioisotope R&D, Korea Atomic Energy Research Institute, Daejeon 305-600, Republic of Korea

Received 19 February 2016; Revised 18 August 2016; Accepted 25 October 2016

Academic Editor: Marinella Striccoli

Copyright © 2016 Eun-Young Jung et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In order to detect low level glucose concentration, an electrochemiluminescence (ECL) biosensor based on TGA-capped CdSe quantum dots (QDs) was fabricated by the immobilization of CdSe QDs after modifying the surface of a glassy carbon electrode (GCE) with 4-aminothiophenol diazonium salts by the electrochemical method. For the detection of glucose concentration, glucose oxidase (GOD) was immobilized onto the fabricated CdSe QDs-modified electrode. The fabricated ECL biosensor based on TGA-capped CdSe QDs was characterized using a scanning electron microscope (SEM), UV-vis spectrophotometry, transmission electron microscopy (TEM), a fluorescence spectrometer (PL), and cyclic voltammetry (CV). The fabricated ECL biosensor based on TGA-capped CdSe QDs is suitable for the detection of glucose concentrations in real human blood samples.