Penetration and Silencing Activity of VEGF Dicer Substrate siRNA Vectorized by Chitosan Nanoparticles in Monolayer Culture and a Solid Tumor Model<i> In Vitro</i> for Potential Application in Tumor Therapy

<div>(a) VEGF mRNA expression in MCLs of DLD-1 cells of untreated MCLs (A), MCLs exposed to naked DsiRNA (B), DsiRNA-CS nanoparticles at 20 pmol (C and D), and 80 pmol (E and F) for 24 and 48 h incubations, respectively. (b) The level of VEGF protein in MCLs after exposure to DsiRNA-CS nanoparticles for 24 and 48 h.</div>

Journal of Nanomaterials

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Figure 10

Figure 10: Penetration and Silencing Activity of VEGF Dicer Substrate siRNA Vectorized by Chitosan Nanoparticles in Monolayer Culture and a Solid Tumor Model<i> In Vitro</i> for Potential Application in Tumor Therapy 

Figure 10 | Penetration and Silencing Activity of VEGF Dicer Substrate siRNA Vectorized by Chitosan Nanoparticles in Monolayer Culture and a Solid Tumor Model In Vitro for Potential Application in Tumor Therapy 