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Journal of Nanomaterials
Volume 2016, Article ID 7372306, 13 pages
http://dx.doi.org/10.1155/2016/7372306
Review Article

Niosomes as Nanoparticular Drug Carriers: Fundamentals and Recent Applications

Institute for Technical Chemistry, Leibniz University Hannover, 30167 Hannover, Germany

Received 21 April 2016; Accepted 23 May 2016

Academic Editor: Lei Liu

Copyright © 2016 Didem Ag Seleci et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Drug delivery systems are defined as formulations aiming for transportation of a drug to the desired area of action within the body. The basic component of drug delivery systems is an appropriate carrier that protects the drug from rapid degradation or clearance and thereby enhances drug concentration in target tissues. Based on their biodegradable, biocompatible, and nonimmunogenic structure, niosomes are promising drug carriers that are formed by self-association of nonionic surfactants and cholesterol in an aqueous phase. In recent years, numerous research articles have been published in scientific journals reporting the potential of niosomes to serve as a carrier for the delivery of different types of drugs. The present review describes preparation methods, characterization techniques, and recent studies on niosomal drug delivery systems and also gives up to date information regarding recent applications of niosomes in drug delivery.