Niosomes as Nanoparticular Drug Carriers: Fundamentals and Recent Applications

Table 3

Recent studies on niosomes in drug delivery.

Type of the drug	Name of the drug	Composition	Experimental model	Year	References
Angiotensin receptor blockers	Candesartan cilexetil	Span 60, cholesterol, dicetyl phosphate, maltodextrin	In vitro dissolution test for proniosomal tablets, in vivo evaluation of proniosomal tablets, pharmacokinetic analysis	2016	[36]
Anti-inflammatory	Naproxen	Tween 80, Tween 20, cholesterol	In vitro drug release study, preformulation study	2016	[37]
	Dexamethasone	Span 60, cholesterol	Characterization of niosomes, in vitro release studies, stability test	2015	[38]
Antibacterial	Moxifloxacin	Tween 60, cholesterol	In vitro release studies, antimicrobial activity	2016	[39]
	Cefixime	C-Glycoside derivative surfactant, cholesterol	In vitro release study, biocompatibility and bioavailability studies using experimental animals	2016	[21]
Anticancer	Doxorubicin	Span 60, cholesterol, dicetyl phosphate, N-lauryl glucosamine	Optimization studies for formulation, skin irritancy, histopathological investigation of rat skin	2016	[35]
	Paclitaxel	Span 40, cholesterol, dicetyl phosphate	Formulation studies, Pharmacokinetic and tissue distribution studies	2015	[6]
Antiviral	Nevirapine	Tyloxapol, cholesterol	Diffusion kinetics of drug, microviscosity studies, in vitro release study	2015	[8]
H2 receptor antagonist	Famotidine	Span 60, cholesterol	Kinetic analysis of drug-release profiles, ex vivo permeability study	2016	[40]