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Journal of Nanomaterials
Volume 2016, Article ID 7614753, 10 pages
http://dx.doi.org/10.1155/2016/7614753
Review Article

Certain Aspects of Silver and Silver Nanoparticles in Wound Care: A Minireview

1Department of Neuropeptides, Mossakowski Medical Research Centre, Polish Academy of Science, 5 Pawinskiego Street, 02-106 Warsaw, Poland
2Department of Dermatology, Medical University of Warsaw, 82A Koszykowa Street, 02-008 Warsaw, Poland

Received 2 November 2015; Accepted 11 January 2016

Academic Editor: Piersandro Pallavicini

Copyright © 2016 Marek Konop et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Resistance to antimicrobial agents by pathogenic bacteria has emerged in recent years and is a major health problem. In this context silver and silver nanoparticles (AgNP) have been known to have inhibitory and bactericidal effects and was used throughout history for treatment of skin ulcer, bone fracture, and supporting wound healing. In all of these applications prevention and treatment of bacterial colonized/infected wounds are critical. In this context silver and its derivatives play an important role in health care. Silver is widely used in clinical practice in the form of silver nitrate and/or silver sulfadiazine. In the last few years silver nanoparticles entered into clinical practice as both antimicrobial and antifungal agents. In addition, nanosilver is used in coating medical devices (catheters) and as component of wound dressings. In this paper we present summarized information about silver and nanoparticles made of silver in the context of their useful properties, especially antibacterial ones, being of a great interest for researchers and clinicians.