Improved Delivery of Caffeic Acid through Liposomal Encapsulation

Table 3

Permeability results obtained for free caffeic acid and liposomal caffeic acid for the permeation through pig ear epidermis.

Formulation	Study period (h)	Percent skin permeation (%)	Percent skin deposition (%)	average (10^−3 cm min^−1)
Free caffeic acid	7	5.3 ± 1.91	6.38 ± 3.10	1.33
Liposomal caffeic acid	7	41.8 ± 1.58	2.0 ± 0.02	28.19