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Journal of Nanomaterials
Volume 2017, Article ID 1985942, 12 pages
Review Article

Application of Nanomaterials in Stem Cell Regenerative Medicine of Orthopedic Surgery

1Department of Orthopedics, The Second Hospital of Jilin University, Changchun, Jilin, China
2Jilin University School of Pharmaceutical Sciences, Changchun, Jilin, China
3China-Japan Union Hospital of Jilin University, Changchun, Jilin, China
4Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, LA, USA
5State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, Jilin, China

Correspondence should be addressed to Yudan Yang; nc.ude.ulj@naduygnay

Received 27 January 2017; Accepted 8 March 2017; Published 6 July 2017

Academic Editor: Jian Zhong

Copyright © 2017 Su Pan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Regenerative medicine aims to achieve functional rehabilitation of tissue or cells injured through wound, disease, or aging. Recent findings suggest that nanotechnology provides advanced biomaterials with specified morphologies which can create a nanoscale extracellular environment capable of promoting the adhesion and proliferation of stem cells and accelerating stem cell differentiation in a controlled manner in tissue engineering. This review summarizes the biological effects of nanomaterials and their regenerative medicine applications in orthopedic surgery research, including bone, cartilage, tendons, and nerve tissue engineering.