TY - JOUR A2 - Zhang, Renyun AU - Kozlovskiy, A. L. AU - Korolkov, I. V. AU - Kalkabay, G. AU - Ibragimova, M. A. AU - Ibrayeva, A. D. AU - Zdorovets, M. V. AU - Mikulich, V. S. AU - Yakimchuk, D. V. AU - Shumskaya, A. E. AU - Kaniukov, E. Yu. PY - 2017 DA - 2017/05/07 TI - Comprehensive Study of Ni Nanotubes for Bioapplications: From Synthesis to Payloads Attaching SP - 3060972 VL - 2017 AB - Due to the Ni nanotubes’ shape anisotropy, low specific density, large specific surface, and uniform magnetic field, they have been offered as carriers for targeted delivery of drug or protein and the process of their formation from synthesis stage to the stage of surface modification and protein attaching has been demonstrated. Some steps to hasten their biomedical application have been applied. First, to have full control over the carrier dimensions and structure parameters, electrodeposition method in pores of polyethylene terephthalate template has been applied. Second, to understand the scope of Ni nanostructures application, their degradation in media with different acidity has been studied. Third, to improve the biocompatibility and to make payloads attachment possible, nanotubes surface modification with organosilicon compound has been carried out. At last, the scheme of protein attaching to the nanostructure surface has been developed and the binding process was demonstrated as an example of the bovine serum albumin. SN - 1687-4110 UR - https://doi.org/10.1155/2017/3060972 DO - 10.1155/2017/3060972 JF - Journal of Nanomaterials PB - Hindawi KW - ER -