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Journal of Nanomaterials
Volume 2017 (2017), Article ID 5107485, 11 pages
Research Article

Heterogeneous Responses of Ovarian Cancer Cells to Silver Nanoparticles as a Single Agent and in Combination with Cisplatin

1Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA
2Salem College, Winston-Salem, NC 27101, USA
3Comprehensive Cancer Center of Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA

Correspondence should be addressed to Ravi N. Singh

Received 18 January 2017; Accepted 26 March 2017; Published 26 April 2017

Academic Editor: Ilaria Fratoddi

Copyright © 2017 Cale D. Fahrenholtz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure 1: (A) A2780, SKOV3 and OVCAR3 cells were seeded and allowed to attach overnight. The following day cells were treated with AgNP (0-100 µg/ml) for 24 hours. Cell viability was assessed by MTT assay. Data is shown as percent viability compared to vehicle treated cells ± standard deviation. (B) Cells were seeded as above and treated with buthionine sulfoxide or vehicle for 24 hours. Fold GSH was assessed and is shown relative to vehicle treated cells ± standard deviation.

Supplementary Table 1: Data supplied by the manufacturer (Nanocomposix) of the AgNP used in this study are shown.

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