Research Article
Biocompatibility and Toxicity of Polylactic Acid/Ferrosoferric Oxide Nanomagnetic Microsphere
Table 4
Results of micronucleus test of PLA/Fe
3O
4 nanomagnetic fluid (
).
| Group | Numbers of polychromatocytes | Numbers of micronucleuses in polychromatocytes | Micronucleus rates (%) |
| Negative control (physiological saline) | 10000 | 26 | 24 | 5.00 g/Kg PLA/Fe3O4 nanomagnetic fluid | 10000 | 24 | 23 | 4.00 g/Kg PLA/Fe3O4 nanomagnetic fluid | 10000 | 22 | 21 | 2.50 g/Kg PLA/Fe3O4 nanomagnetic fluid | 10000 | 20 | 19 | 1.25g/Kg PLA/Fe3O4 nanomagnetic fluid | 10000 | 21 | 22 | Positive control (cyclophosphamide) | 10000 | 291 | 289 |
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