Research Article

Biodistribution and Acute Toxicity of Intravenous Multifunctional 125I-Radiolabeled Fe3O4-Ag Heterodimer Nanoparticles in Mice

Table 1

Haematological and serum biochemistry parameters of the mice exposed to Fe3O4-Ag125I. Data represent means ± SD ().

ALB (g/L)ALT (U/L)AST (U/L)ALP (U/L)Ur (mmol/L)Cr (μmol/L)WBC (109/L)RBC (1012/L)HB (g/L)PLT (109/L)

Control27.32 ± 0.9815.32 ± 10.34189.33 ± 32.1171.12 ± 22.968.03 ± 1.6921.52 ± 4.743.94 ± 0.748.40 ± 0.93143.00 ± 5.66759.50 ± 65.76
Fe3O4-Ag125I26.14 ± 2.4830.93 ± 14.41256.35 ± 56.2869.63 ± 15.0510.27 ± 1.9835.16 ± 30.213.81 ± 1.397.21 ± 0.42120.50 ± 3.54629.00 ± 131.52

compared with control group. ALB: albumin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; Ur: urea; Cr: creatinine; WBC: white blood cell count; RBC: red blood cell count; HB: hemoglobin; PLT: platelet.