Exosomes: A Paradigm in Drug Development against Cancer and Infectious Diseases

Table 2

Recent reported methods for molecular profiling of exosomes.

Method	Source	Application	Explanations	Ref.
Combined colloidal gold nanoplasmonics and SPR	Serum	Oncology	Detection at molar level, Showed presence of 4-fold exosomes in MM patients than normal	[14]
Microfluidic	Plasma	Cancer as well as non-cancerous diseases	Enhanced and minimal invasive detection,	[15]
SPR	Serum	Oncology	Quantification of the proportion of CREs within the bulk exosome population	[16]
NTA	Whole blood sample	Oncology	Enriched level of MDR-1, MDR-3, endophilin-A2, and PABP4 in resistance prostate cancer cells (DU145)	[17]
Metal Nanoparticle	Serum	Oncology	Microsome and exosome detection, detection of two surface markers on exosome	[18]
Dual-wavelength SPR	Synthetic	Drug development	Vesicles carrying marker CD63 link to not greater than 10% of the vesicles in sample.	[19]