The Recent Advances of Magnetic Nanoparticles in Medicine

Table 1

Frequently used compounds to surfacely modify magnetic NPs.

Modified compounds	Advantages	Applications
PEG [12]	Enhanced water solubility of NPs, reduced RES phagocytosis, and increased blood circulation time	MRI, tumor diagnosis, and treatment
PEI	Good biocompatibility	Gene and drug vectors
Polyvinyl alcohol (PVA)	Elevated stability and reduced particle aggregation	MRI, vectors, and bioseparation
Glucan	Excellent stability and extended in vivo circulation time	Drug vectors
Chitosan [13]	Good stability and biocompatibility	Vector, thermotherapy
Liposome [14]	Good biocompatibility	Tumor treatment, thermotherapy, and MRI
FA [15]	Good biocompatibility, essential small-molecule vitamin for the human body	Targeted receptors, diagnosis, and treatment of tumors (breast cancer, cervical cancer, and ovarian cancer)
Gold [16, 17]	Biocompatibility can provide optical property and magnetism for biological application	Tumor diagnosis and MRI