Recent Advances in the Synthesis, Properties, and Biological Applications of Platinum Nanoclusters

Figure 14

(a) Schematic apoptosis mechanism of cisplatin and inhibiting cisplatin-induced apoptosis. Red dotted line means that antiapoptotic factors counteract caspase activation. (b) Schematic apoptosis mechanism of Pt NCs. Abundant oxidized Pt ions and Pt NCs coordinate the DNA damage activating the p53 pathway (reprinted with permission from [204], Copyright 2017, Elsevier).

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