Recent Advances in the Synthesis, Properties, and Biological Applications of Platinum Nanoclusters

Figure 15

(a) TEM photograph of Pt NCs; the scale bar is 50 nm. (b) HR-TEM photograph shows that the NCs are formed via self-assembled NPs (scale bar is 5 nm). Inset corresponds the selected area electron diffraction (SAED) pattern. (c) MIC determination by resazurin microtiter plate assay (REMA) for Pt NCs towards Salmonella typhi and (d) zone of inhibition assay at MIC (12.5 μM). Fluorescence microscopy photographs of Salmonella typhi double stained with acridine orange (AO, membrane, green) and propidium iodide (PI, nucleic acid, red) for (e) untreated cells and (f) 12.5 μM Pt NCs treated. SEM photographs of (g) untreated cells and (h) 12.5 μM Pt NCs treated (reprinted major modification with permission from [206], Copyright 2018, Elsevier).

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