Hydroxyapatite Nanoparticle Coating on Polymer for Constructing Effective Biointeractive Interfaces

Figure 10

Study of hepatocyte cell aggregation and adhesion at HAp NPs covered with SU-8 polymer micropatterns by nano/microfabrication techniques. (a) Schematic illustration of the micropatterning process to obtain SU-8/HAp nanocrystals/Au/Ti/silica substrate and the subsequent cells adhered on HAp surface, (b) optical microscopic image of a cell, (c) 3D graphics image of the cell, (d) AFM topographic, and (e) phase shift images of the cell and HAp nanocrystalline surfaces. Reprinted with permission from [239], M. Tagaya et al., Macromol. Biosci. 11, 1586—1593 (2011) © 2011, Wiley-VCH.

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