Tinidazole Delivery Improved by Nanosized Minicells Originated from Leuconostoc mesenteroides

Table 4

The representative encapsulation quantum obtained in the surface plot.

Tinidazole concentration (mg/ml)	Volume of minicell (/ml)
	10	12.25	14.5	16.75	19	21.25	23.5	25.75	28	30.25	32.5	34.75	37
0.1	0.099164496	0.09913247	0.099102822	0.099075553	0.099050663	0.099028151	0.099008018	0.098990264	0.098974888	0.098961891	0.098951272	0.098943032	0.098937171
0.12	0.119144695	0.119112271	0.119082226	0.119054559	0.119029271	0.119006362	0.118985831	0.118967679	0.118951905	0.11893851	0.118927494	0.118918856	0.118912597
0.14	0.139126341	0.139093519	0.139063076	0.139035012	0.139009326	0.138986019	0.13896509	0.13894654	0.138930368	0.138916576	0.138905162	0.138896126	0.138889469
0.16	0.159109432	0.159076213	0.159045372	0.15901691	0.158990826	0.158967121	0.158945795	0.158926847	0.158910278	0.158896087	0.158884275	0.158874842	0.158867787
0.18	0.17909397	0.179060353	0.179029114	0.179000254	0.178973773	0.17894967	0.178927946	0.178908601	0.178891634	0.178877045	0.178864836	0.178855004	0.178847552
0.2	0.199079954	0.199045939	0.199014303	0.198985045	0.198958166	0.198933665	0.198911543	0.1988918	0.198874435	0.198859449	0.198846842	0.198836613	0.198828763
0.22	0.219067384	0.219032972	0.219000937	0.218971282	0.218944005	0.218919107	0.218896587	0.218876446	0.218858683	0.2188433	0.218830294	0.218819668	0.21881142
0.24	0.239056261	0.23902145	0.238989018	0.238958965	0.23893129	0.238905994	0.238883077	0.238862538	0.238844377	0.238828596	0.238815193	0.238804168	0.238795523
0.26	0.259046583	0.259011375	0.258978545	0.258948094	0.258920022	0.258894328	0.258871012	0.258850076	0.258831518	0.258815338	0.258801538	0.258790115	0.258781072
0.28	0.279038352	0.279002746	0.278969518	0.278938669	0.278910199	0.278884107	0.278860394	0.27883906	0.278820104	0.278803527	0.278789328	0.278777508	0.278768067
0.3	0.299031566	0.298995563	0.298961937	0.298930691	0.298901823	0.298875333	0.298851223	0.29882949	0.298810137	0.298793162	0.298778566	0.298766348	0.298756509
0.32	0.319026227	0.318989826	0.318955803	0.318924158	0.318894893	0.318868005	0.318843497	0.318821367	0.318801616	0.318784243	0.318769249	0.318756633	0.318746396
0.34	0.339022334	0.338985535	0.338951114	0.338919072	0.338889409	0.338862124	0.338837217	0.33881469	0.33879454	0.33877677	0.338761378	0.338748365	0.33873773
0.36	0.359019888	0.35898269	0.358947872	0.358915432	0.358885371	0.358857688	0.358832384	0.358809458	0.358788912	0.358770743	0.358754954	0.358741543	0.35873051
0.38	0.379018887	0.378981292	0.378946076	0.378913238	0.378882779	0.378854699	0.378828997	0.378805673	0.378784729	0.378766163	0.378749975	0.378736167	0.378724736
0.4	0.399019333	0.39898134	0.398945726	0.39891249	0.398881634	0.398853155	0.398827056	0.398803335	0.398781992	0.398763028	0.398746443	0.398732237	0.398720409
0.42	0.419021224	0.418982834	0.418946822	0.418913189	0.418881934	0.418853058	0.418826561	0.418802442	0.418780702	0.41876134	0.418744357	0.418729753	0.418717527
0.44	0.439024562	0.438985774	0.438949364	0.438915333	0.438883681	0.438854407	0.438827512	0.438802995	0.438780857	0.438761098	0.438743717	0.438728715	0.438716092
0.46	0.459029346	0.45899016	0.458953353	0.458918924	0.458886874	0.458857202	0.458829909	0.458804995	0.458782459	0.458762302	0.458744524	0.458729124	0.458716103
0.48	0.479035576	0.478995993	0.478958788	0.478923961	0.478891513	0.478861444	0.478833753	0.478808441	0.478785507	0.478764952	0.478746776	0.478730979	0.478717559
0.5	0.499043253	0.499003271	0.498965668	0.498930444	0.498897598	0.498867131	0.498839043	0.498813333	0.498790002	0.498769049	0.498750475	0.498734279	0.498720463
0.52	0.519052375	0.519011996	0.518973995	0.518938373	0.51890513	0.518874265	0.518845779	0.518819671	0.518795942	0.518774591	0.51875562	0.518739026	0.518724812
0.54	0.539062944	0.539022167	0.538983768	0.538947749	0.538914107	0.538882845	0.538853961	0.538827455	0.538803328	0.53878158	0.538762211	0.53874522	0.538730607
0.56	0.559074959	0.559033784	0.558994988	0.55895857	0.558924531	0.558892871	0.558863589	0.558836686	0.558812161	0.558790015	0.558770248	0.558752859	0.558737849
0.58	0.57908842	0.579046847	0.579007653	0.578970838	0.578936401	0.578904343	0.578874663	0.578847362	0.57882244	0.578799896	0.578779731	0.578761945	0.578746537
0.6	0.599103327	0.599061357	0.599021765	0.598984552	0.598949717	0.598917261	0.598887184	0.598859485	0.598834165	0.598811223	0.598790661	0.598772476	0.598756671
0.62	0.61911968	0.619077312	0.619037323	0.618999712	0.618964479	0.618931626	0.618901151	0.618873054	0.618847336	0.618823997	0.618803036	0.618784454	0.618768251
0.64	0.63913748	0.639094714	0.639054327	0.639016318	0.638980688	0.638947436	0.638916563	0.638888069	0.638861953	0.638838216	0.638816858	0.638797878	0.638781277
0.66	0.659156725	0.659113562	0.659072777	0.65903437	0.658998342	0.658964693	0.658933422	0.65890453	0.658878017	0.658853882	0.658832126	0.658812748	0.658795749
0.68	0.679177417	0.679133856	0.679092673	0.679053869	0.679017443	0.678983396	0.678951728	0.678922438	0.678895527	0.678870994	0.67884884	0.678829065	0.678811668
0.7	0.699199555	0.699155596	0.699114015	0.699074813	0.69903799	0.699003545	0.698971479	0.698941791	0.698914482	0.698889552	0.698867	0.698846827	0.698829032
0.72	0.719223139	0.719178782	0.719136804	0.719097204	0.719059983	0.71902514	0.718992676	0.718962591	0.718934884	0.718909556	0.718886607	0.718866036	0.718847843
0.74	0.73924817	0.739203415	0.739161039	0.739121041	0.739083422	0.739048182	0.73901532	0.738984837	0.738956732	0.738931006	0.738907659	0.73888669	0.7388681
0.76	0.759274646	0.759229494	0.75918672	0.759146324	0.759108307	0.759072669	0.75903941	0.759008529	0.758980027	0.758953903	0.758930158	0.758908791	0.758889804
0.78	0.779302569	0.779257018	0.779213847	0.779173054	0.779134639	0.779098603	0.779064946	0.779033667	0.779004767	0.778978246	0.778954103	0.778932339	0.778912953
0.8	0.799331937	0.799285989	0.79924242	0.799201229	0.799162417	0.799125983	0.799091928	0.799060252	0.799030954	0.799004034	0.798979494	0.798957332	0.798937548
0.82	0.819362752	0.819316406	0.819272439	0.819230851	0.819191641	0.819154809	0.819120356	0.819088282	0.819058586	0.819031269	0.819006331	0.818983771	0.81896359
0.84	0.839395013	0.83934827	0.839303905	0.839261918	0.839222311	0.839185081	0.839150231	0.839117759	0.839087665	0.839059951	0.839034614	0.839011657	0.838991078
0.86	0.859428721	0.859381579	0.859336816	0.859294432	0.859254427	0.8592168	0.859181551	0.859148682	0.85911819	0.859090078	0.859064344	0.859040989	0.859020012
0.88	0.879463874	0.879416335	0.879371174	0.879328392	0.879287989	0.879249964	0.879214318	0.879181051	0.879150162	0.879121651	0.87909552	0.879071767	0.879050392
0.9	0.899500474	0.899452537	0.899406978	0.899363799	0.899322997	0.899284575	0.899248531	0.899214866	0.899183579	0.899154671	0.899128141	0.899103991	0.899082218