Lactoferrin Coating Improves the Antibacterial and Osteogenic Properties of Alkali-Treated Titanium with Nanonetwork Structures
Evaluation of in vitro osteogenic induction ability of rBMMSCs: (a) cell adhesion of rBMMSCs on sample disks; (b) expression of osteogenesis-related genes in cells grown on sample disks; (c) ALP activity, calcium deposition, and production of OCN in cells grown on sample disks. ;;. TNS: titanium with nanonetwork structures; TNS-LF: titanium with nanonetwork structures coated with lactoferrin; rBMMSCs: rat bone marrow mesenchymal stem cells; Runx2: runt-related transcription factor 2; ALP: alkaline phosphatase; BMP-2:bone morphogenetic protein 2; OPN: osteopontin; OCN: osteocalcin.
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