Development of a BCS Class II Drug Microemulsion for Oral Delivery: Design, Optimization, and Evaluation

Table 1

Variables used in the factorial design.

Independent variables (factors)	Levels used, actuel (coded)
	Low (-1)	Medium (0)	High (+1)
	8.6	24.3	40.0
	0.4	5.0	2.7
Dependent variables (responses)	Goals
	Low	High	Goal
(nm)	51	324	Minimize
(mV)	-8	-17.9	Maximize (absolute value)