Research Article
Development of a BCS Class II Drug Microemulsion for Oral Delivery: Design, Optimization, and Evaluation
| Run | Formulation plan | Responses | % S | % CoS | % oil | % water | | |
| 1 | 6.45 | 2.15 | 0.40 | 91 | 228 | -9.78 | 2 | 30 | 10 | 0.40 | 59.60 | 324 | -16.16 | 3 | 6.45 | 2.15 | 5.00 | 86.40 | 123 | -10.6 | 4 | 30 | 10 | 5.00 | 55.00 | 221 | -8 | 5 | 6.45 | 2.15 | 2.70 | 88.70 | 105 | -11.94 | 6 | 30 | 10 | 2.70 | 57.30 | 170 | -11.32 | 7 | 18.225 | 6.075 | 0.40 | 75.30 | 200 | -14.33 | 8 | 18.225 | 6.075 | 5.00 | 70.70 | 51 | -8.67 | 9 | 18.225 | 6.075 | 2.70 | 73.00 | 55 | -17.6 | 10 | 18.225 | 6.075 | 2.70 | 73.00 | 56 | -17.9 | 11 | 18.225 | 6.075 | 2.70 | 73.00 | 54 | -17.5 | 12 | 18.225 | 6.075 | 2.70 | 73.00 | 53.00 | -17.65 |
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