Application of Nanomaterial in Hydrogels Related to Wound Healing

Table 1

The role of nanotechnology in wound hydrogel.

Effective	Mechanism
Improving mechanical properties	In situ polymerization [59], electrospinning technology [60], casting and coordination interaction [61–64]
Drug release	Three-tier structure [65] and embedding [66]
	Cross-linked and direct interaction [26, 49, 58, 67–70]
Antibacterial effect [39]	Interfering with DNA replication and RNA production
	Destroy cell membranes
	Interference with cellular respiration
	Change enzyme conformation and inactivate enzyme activity
Increased adhesion	Covalent coupling [71] and noncovalent complex [60, 72]