Application of Nanomaterial in Hydrogels Related to Wound Healing

Table 2

The common materials used to design nanohydrogel for wound repair.

Type	Advantage	Application
Collagen-based hydrogel	Forms microenvironment similar to extracellular mechanisms	Spontaneous migration of fibroblasts [73], antibacterial [26, 58, 67], and improve mechanical properties [61]
Gelatin-based hydrogel	Good biocompatibility, solubility	Improved mechanical properties [59], adhesion [71], antibacterial [68], drug release [65], and regeneration [71]
Fibrin-based hydrogel	Good adhesion, biocompatibility	Increase mechanical strength [62, 63] and regeneration [62]
Chitosan-based hydrogel	Good hemostatic properties	Increase mechanical strength [72], adhesion [60], antibacterial [74], and drug release [66]
Cellulose-based hydrogel	Most distributed, content	Increase the scope of application [75], antibacterial [69, 75], drug release [69], and regeneration [49]
Hyaluronic acid-based hydrogel	Good hydrophilicity, biocompatibility	Increase mechanical strength [64] and regeneration [76]
Polyethylene glycol-based hydrogel	High molecular polymer	Promote cell proliferation [77], antibacterial [77], and drug release [70]