The Aptamer Functionalized Nanocomposite Used for Prostate Cancer Diagnosis and Therapy

Figure 4

Schematic illustration of tumor-targeting nanoparticles. (a) Passive targeting. (EPR effect of nanoparticles). Extravasation of nanoparticles through fenestrated vasculature leads to passive targeting of tumor tissue; (b) active targeting. Ligands (aptamers, antibodies, small molecules, etc.) linked with nanoparticles that bind to receptors overexpressed by tumor cells.

(a)

(b)