Journal of Nanomaterials

Nanomaterials for Cancer Diagnosis and Therapy


Publishing date
01 Apr 2010
Status
Published
Submission deadline
01 Oct 2009

Lead Editor
Guest Editors

1Laboratory of Advanced Materials, Department of Macromolecular Science, Fudan University, Shanghai 200438, China

2The Institute for Advanced Materials and Nano Biomedicine, Tongji University, Shanghai 200092, China


Nanomaterials for Cancer Diagnosis and Therapy

Description

Integration of nanotechnology into the treatment of various diseases such as cancers represents a mainstream in the current and future research due to the limitations of traditional clinical diagnosis and therapy. The early detection of cancer has been universally accepted to be essential for treatment. However, it remains challenging to detect tumors at an early stage. For instance, the goal of molecular imaging in breast cancer is to diagnose the tumor with approximately 100–1000 cells, compared to the traditional techniques which may require more than a million cells for accurate clinical diagnosis. On another hand, anticancer drugs are designed to simply kill cancer cells, and their entrance into healthy organs or tissues is undesirable due to the severe side effects. In addition, the rapid and widespread distribution of anticancer drugs into nontargeted organs and tissues requires a lot of drugs with high cost. These difficulties have largely limited the successful therapy of cancer.

Nanomaterials are anticipated to revolutionize the cancer diagnosis and therapy. The development of multifunctional polymeric nanoparticles allows for the early detection of cancers. The construction of intelligent polymeric nanosystems can be used as controlled delivery vehicles to improve the therapy efficiency of anticancer drugs, that is, such vehicles are capable of delivering drugs to predetermined locations and then releasing them with preprogrammed rates in response to the changes of environmental conditions such as pH and temperature. Besides polymers, these nanomaterials can also be composed of supraparamagnetic iron oxide, carbon nanotube, metallic nanoshell, core-shell aggregate, or composites. These nanomaterials represent new directions for more effective drug administration in cancer.

This special issue of the Journal of Nanomaterials will cover a wide range of nanomaterials for cancer diagnosis and therapy. It will mainly focus on the preparations, characterizations, functionalizations, and properties of nanoparticles, nanostructured coatings, films, membranes, nanoporous materials, nanocomposites, and biomedical devices. Fundamental understanding of the basic mechanisms on material and biological processes related to the unique nanoscale properties of the materials will be the highlights of this special issue.

Papers are solicited in, but not limited to, the following areas:

  • Synthesis and functionalization of polymer nanoparticle/nanomicelle/nanocomplex
  • Polymer nanoparticle/hydrogl for drug delivery
  • Synthesis of intelligent nanogel
  • Hydrogel in nanoscale sensing
  • Supraparamagnetic nanoparticle for magnetic resonance imaging applications
  • Carbon nanotube-based devices for drug delivery
  • Core-shell nanoparticle for molecular imaging
  • Metallic nanoshell for drug delivery
  • Nanoporous and nanoscaled materials for drug delivery
  • Nanotechnologies for targeted delivery
  • Controlled drug-delivery nanovehicles
  • Biopolymers for drug/gene delivery and therapy
  • Injectable hydrogels for tissue regenerations
  • Bionanoparticles and their biomedical applications
  • Nanomaterials for biosensors
  • Toxicology of nanomaterials

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jnm/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2010
  • - Article ID 592901
  • - Editorial

Nanomaterials for Cancer Diagnosis and Therapy

Huisheng Peng | Chao Lin
  • Special Issue
  • - Volume 2010
  • - Article ID 937684
  • - Research Article

Detection of Thyroid Carcinoma Antigen with Quantum Dots and Monoclonal IgM Antibody (JT-95) System

Kouki Fujioka | Noriyoshi Manabe | ... | Yoshinobu Manome
  • Special Issue
  • - Volume 2010
  • - Article ID 491471
  • - Research Article

Development of Near Infrared-Fluorescent Nanophosphors and Applications for Cancer Diagnosis and Therapy

Tamotsu Zako | Hiroshi Hyodo | ... | Kohei Soga
  • Special Issue
  • - Volume 2010
  • - Article ID 910434
  • - Research Article

Uptake and Cytotoxicity of Ce(IV) Doped TiO2 Nanoparticles in Human Hepatocyte Cell Line L02

Jian Mao | Long Wang | ... | Mingjing Tu
  • Special Issue
  • - Volume 2010
  • - Article ID 780171
  • - Research Article

Controlled Release of Doxorubicin from Doxorubicin/-Polyglutamic Acid Ionic Complex

Bhavik Manocha | Argyrios Margaritis
  • Special Issue
  • - Volume 2010
  • - Article ID 232017
  • - Research Article

Electrospun Poly(L-Lactide-co-ε-Caprolactone)/Polyethylene Oxide/Hydroxyapaite Nanofibrous Membrane for Guided Bone Regeneration

Gang Wang | Tianbin Ren | ... | Jiansheng Su
  • Special Issue
  • - Volume 2010
  • - Article ID 676839
  • - Review Article

Application of Quantum Dots-Based Biotechnology in Cancer Diagnosis: Current Status and Future Perspectives

Chun-Wei Peng | Yan Li
  • Special Issue
  • - Volume 2010
  • - Article ID 796303
  • - Review Article

Cancer Therapy Based on Nanomaterials and Nanocarrier Systems

Weili Qiao | Bochu Wang | ... | Pengyu Shao
  • Special Issue
  • - Volume 2010
  • - Article ID 825363
  • - Research Article

Nanoconjugate Platforms Development Based in Poly( ,L-Malic Acid) Methyl Esters for Tumor Drug Delivery

José Portilla-Arias | Rameshwar Patil | ... | Eggehard Holler
  • Special Issue
  • - Volume 2010
  • - Article ID 583970
  • - Research Article

Nanoprodrugs of NSAIDs Inhibit the Growth of U87-MG Glioma Cells

Bong-Seop Lee | Xiangpeng Yuan | ... | John S. Yu
Journal of Nanomaterials
 Journal metrics
Acceptance rate49%
Submission to final decision69 days
Acceptance to publication29 days
CiteScore3.200
Impact Factor1.980
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