Journal of Nanomaterials

Nanotechnology-Based Fabrication and Application of Biomolecule-Immobilized Microscale Systems for Bioanalysis and Pharmaceutical Analysis


Publishing date
01 Jan 2022
Status
Closed
Submission deadline
20 Aug 2021

Lead Editor

1Changzhou University, Changzhou, China

2University of Innsbruck, Innsbruck, Austria

This issue is now closed for submissions.
More articles will be published in the near future.

Nanotechnology-Based Fabrication and Application of Biomolecule-Immobilized Microscale Systems for Bioanalysis and Pharmaceutical Analysis

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Nanomaterials with unique properties are widely used in modern analytical chemistry. Significant advances in nanotechnology have paved the way for the introduction of a large number of new materials and devices with desirable properties for numerous applications. Biomolecule-immobilized microscale systems present promising potential for analysis based on their reduced reagent consumption, improved analysis speed, automated processing, and high throughput. To increase biomolecule binding capacity, improve biomolecule activity and stability, enhance renewability, and develop easy-to-operate procedures, strategies utilizing nanomaterials are attracting increasing attention.

Various nanomaterials, including carbon, gold, and silica nanoparticles, and metal-oxide nanomaterials have been used to prepare state-of-the-art DNA-, protein-, and polysaccharide-immobilized microscale systems. However, the main challenge is to better understand the mechanisms of application of nanomaterials to improve device performance. In the field of analysis, choosing suitable nanomaterials for fabricating novel analytical devices is a key research area for studying the above-mentioned challenges. It is also a rapid and reliable way to accelerate research development. One interesting application of nanomaterials is to fabricate DNA-immobilized microscale systems. For instance, a nanomaterial-based strategy is an innovative method for the preparation of DNA aptamer-immobilized capillaries, and gold nanoparticles have been utilized to integrate DNA into capillary- and microchip-based microsystems. The obtained DNA-immobilized microscale systems display desirable performance for affinity analysis and enantioseparation. Protein immobilization is a promising technique for improving protein characteristics, such as stability, activity, and renewability. In addition to gold nanoparticles, various nanomaterials including graphene, polystyrene nanoparticles, poly(glycidyl methacrylate) nanoparticles, and silica nanoparticles also exhibit specific advantages for developing protein-immobilized microscale systems. Nanomaterials provide a satisfactory alternative for developing serum albumin-, antibody-, and enzyme-immobilized microscale systems. For the development of polysaccharide-immobilized microscale systems, nanomaterial-based strategies are a new way of improving chiral separation ability. These proposed biomolecule-immobilized microscale systems have great potential in the field of bioanalysis and pharmaceutical analysis.

The aim of this Special Issue is to collate original research articles providing valuable input on nanomaterial design for the fabrication of DNA-, protein-, and polysaccharide-immobilized microscale systems. Submissions focusing on the development of novel capillary- and microchip-based systems and the improvement of current technologies are also encouraged. Moreover, we hope that this Special Issue increases our understanding of nanotechnology. Review articles discussing the state of the art are also welcome.

Potential topics include but are not limited to the following:

  • Nanomaterials for fabricating DNA aptamer-immobilized microscale systems
  • Nanomaterials for fabricating serum albumin-immobilized microscale systems
  • Nanomaterials for fabricating antibody-immobilized microscale systems
  • Nanomaterials for fabricating enzyme-immobilized microscale systems
  • Nanomaterials for fabricating polysaccharide-immobilized microscale systems
  • Biomolecule-immobilized microscale systems for bioanalysis
  • Biomolecule-immobilized microscale systems for pharmaceutical analysis
  • Nanomaterials for bioanalysis and pharmaceutical analysis

Articles

  • Special Issue
  • - Volume 2021
  • - Article ID 2886450
  • - Research Article

Improvement of Resveratrol Solubility by Complexation with Lactose Using Organic Solvent Spray Drying Technique

Bo Wang | Xinran Sun | ... | Zeneng Cheng
  • Special Issue
  • - Volume 2021
  • - Article ID 4145010
  • - Research Article

Evaluation of Poly(Glycidyl Methacrylate) Nanocoating for Chiral Separation with Glu-β-CD as Chiral Selector in Capillary Electrophoresis

Jin Xu | Xuecheng Sun | ... | Ye Lu
  • Special Issue
  • - Volume 2021
  • - Article ID 9910553
  • - Research Article

A Novel Polyaniline Nanofiber Combined with Toluidine Blue as a Sensitive Detection Platform for Lignin by Raman Spectroscopy

Hui Zhang | Jing Li | ... | Shengquan Liu
  • Special Issue
  • - Volume 2021
  • - Article ID 9932538
  • - Research Article

Methods in Biosynthesis and Characterization of the Antifreeze Protein (AFP) for Potential Blood Cryopreservation

Xiangjian Liu | Haiyan Peng | ... | Songwen Tan
  • Special Issue
  • - Volume 2021
  • - Article ID 9971152
  • - Research Article

Immune-Related Genes: Potential Prognostic Factors and Regulatory Targets for Cervical Carcinoma

Feng Xie | Xiaofeng Liu | ... | Wei Liu
  • Special Issue
  • - Volume 2021
  • - Article ID 9990709
  • - Review Article

A Review of the Material Characteristics, Antifreeze Mechanisms, and Applications of Cryoprotectants (CPAs)

Xiangjian Liu | Yuxin Pan | ... | Songwen Tan
  • Special Issue
  • - Volume 2021
  • - Article ID 9972879
  • - Research Article

Treatment of Gingival Recession with Microinvasive Surgical Technology

Qiong Cao | Ruohuang Lu | ... | Yuehong Wang
Journal of Nanomaterials
 Journal metrics
Acceptance rate49%
Submission to final decision69 days
Acceptance to publication29 days
CiteScore3.800
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Impact Factor2.986
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