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Journal of Nutrition and Metabolism
Volume 2010, Article ID 230501, 4 pages
Clinical Study

Different Types of Resistant Starch Elicit Different Glucose Reponses in Humans

1Human Metabolism Laboratory, Department of Human Nutrition, Kansas State University, Manhattan, KS 66506, USA
2Department of Grain Science and Industry, Kansas State University, Manhattan, KS 66506, USA

Received 6 July 2009; Accepted 4 September 2009

Academic Editor: Michael Pagliassotti

Copyright © 2010 Mark D. Haub et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The purpose of this study was to determine whether different types of resistant starch (RS) elicited different glycemic responses. Eleven healthy subjects consumed solutions containing 30 g of either dextrose (DEX), resistant starch type 2 (RS2), or cross-linked resistant wheat starch type 4 (RS4XL) on three separate occasions, which were assigned randomly. Finger stick blood samples were collected before and over the following two hours and measured for glucose. The incremental area under the curve (iAUC) for the glucose response was calculated for all trials. The two types of resistant starch significantly (P<.05) decreased iAUC compared with DEX. The response with RS4XL was significantly decreased compared with the RS2 trial. These data demonstrate that different types of resistant starch elicit significantly different glycemic responses.