Hop and Acacia Phytochemicals Decreased Lipotoxicity in 3T3-L1 Adipocytes, db/db Mice, and Individuals with Metabolic Syndrome

Table 1

Observed and expected lipogenic response elicited by hops RIAA and acacia PAC in the 3T3-L1 model.

	RIAA  :   PAC at 1  :  5 (wt  :  wt)			RIAA  :  PAC at 1  :  10 (wt  :  wt)
Lipogenic Index *	Observed	Expected	Synergy	Observed	Expected	Synergy
50 (g/mL)	1.05	0.98	Yes	0.99	1.03	No
10	0.96	0.89	Yes	1.00	0.90	Yes
5	0.93	0.90	Yes	1.00	0.90	Yes
1	0.92	0.89	Yes	0.94	0.89	No
Adiponectin Index **
50 (g/mL)	1.27	1.08	Yes	1.29	1.11	Yes
10	0.99	1.25	No	1.07	0.95	Yes
5	1.02	0.92	Yes	0.94	1.06	No
1	1.19	1.07	Yes	1.03	0.94	Yes

ipogenic Index = [optical density/[optical density.
dipogenic Index = [adiponectin/[adiponectin