Journal of Nutrition and Metabolism / 2010 / Article / Tab 3

Clinical Study

Effects of Growth Hormone and Insulin-Like Growth Factor-1 on Postoperative Muscle and Substrate Metabolism

Table 3

Plasma glucose, urea and CRP levels pre- and postoperatively.

D0D1D2D3

Glucose (mmol/L)Control4.9 (4.3–5.4)8.2 (6.2–9.8)*6.6 (5.6–7.2)5.8 (5.3–6.5)
GH4.6 (3.9–5.2)8.2 (6.8–11.1)*8.2 (6.7–10.9)*9.1 (7.0–11.2)*#
GH-IGF-14.8 (4.7–5.2)8.7 (7.3–8.9) **7.4 (6.5–9.9) **7.4 (6.9–12.6) **#

Urea (mmol/L)Control4.0 (3.1–5.2)4.4 (3.1–5.3)3.4 (3.1–3.5)3.4 (3.2–4.1)
GH4.0 (3.1–6.3)3.1 (2.9–5.8)2.3 (1.9–3.5)*2.0 (1.4–2.9)*#
GH-IGF-14.1 (3.5–4.9)4.4 (3.5–4.9)2.5 (2.0–2.9)*1.9 (1.4–2.2) **#

CRP (mg/L)Control7 (5–13)59 (55–91) **104 (94–130) **67 (59–109) **
GH5 (5–14)46 (39–102)*106 (43–145)*69 (29–88)*
GH-IGF-112 (5–20)82 (66–86) **135 (82–155) **91 (53–114) **

*and **indicate a postoperative difference within the groups ( 𝑃 < . 0 5 and 𝑃 < . 0 1 ) as compared to D0, and # indicates a difference between the controls and the groups given growth factors ( 𝑃 < . 0 5 ). Values are given as medians and quartiles.