Journal of Nutrition and Metabolism / 2010 / Article / Tab 7

Clinical Study

Effects of Growth Hormone and Insulin-Like Growth Factor-1 on Postoperative Muscle and Substrate Metabolism

Table 7

Glutathione concentrations and redox-status of glutathione in skeletal muscle (mmol(kg ww muscle)). Total glutathione (tGSH), reduced glutathione (GSH), oxidized glutathione (GSSG), and the redox-status of glutathione (GSH/tGSH).

D0 D3

tGSHControl2.02 (1.78–2.16)1.75 (1.59–1.95) 𝑃 = . 0 6
GH2.03 (1.97–2.43)1.71 (1.36–1.88)*
GH-IGF-11.91 (1.71–1.98)1.62 (1.40–1.79) 𝑃 = . 0 5 1

GSHControl1.67 (1.49–1.86)1.52 (1.30–1.76)
GH1.65 (1.52–2.16)1.45 (1.02–1.74)*
GH-IGF-11.65 (1.50–1.73)1.33 (1.25–1.47)*

GSSGControl0.17 (0.13–0.18)0.13 (0.11–0.16)
GH0.18 (0.10–0.22)0.15 (0.07–0.17)
GH-IGF-10.13 (0.10–0.15)0.15 (0.09–0.18)

GSH/tGSHControl0.83 (0.80–0.88)0.86 (0.82–0.89)
GH0.83 (0.77–0.90)0.86 (0.75–0.91)
GH-IGF-10.85 (0.84–0.90)0.83 (0.81–0.87)

*indicates a postoperative difference within the groups ( 𝑃 < . 0 5 and 𝑃 < . 0 1 ). 𝑃 < . 1 0 are given as numbers. Values are given as median and quartiles.