Figure 12: The biochemical connections between the cytosol and mitochondria of skeletal muscle for the complete oxidation of carbohydrate. Note that the TCA cycle as shown is not complete for all substrates and products. Also, the ATP yield from carbohydrate oxidation is greater for the substrate glycogen than glucose. For skeletal muscle, there are 37 molecules of ATP produced from one Glucose-6-phosphate derived from glycogen, assuming the presence of the glycerol-3-phosphate shuttle.