Coffee Consumption and Cystatin-C-Based Estimated Glomerular
Filtration Rates in Healthy Young Adults: Results of a Clinical Trial
Table 2
Changes in variables according to coffee and green tea consumption.
Coffee
Green tea
Baseline
End of consumption
Change (95% CI)
Baseline
End of consumption
Change (95% CI)
BMI (kg/m2)
21.2 ± 2.5
21.3 ± 2.4
0.1 (0.0–0.2)
21.4 ± 2.5
21.2 ± 2.5
−0.2 (−0.3–0.0)
SBP (mm Hg)
118 ± 16
119 ± 11
0.7 (−5.9–7.4)
121 ± 11
116 ± 9.3*
−0.5 (−9.6–−0.3)
DBP (mm Hg)
75 ± 8.8
77 ± 9.1
2.5 (−1.2–6.2)
78 ± 8.9
76 ± 7.4
−1.7 (−6.9–3.4)
Total cholesterol (mg/dL)
174 ± 22
175 ± 26
1.7 (−5.1–8.6)
176 ± 19
170 ± 22
−5.4 (−12.5–1.7)
HDL-cholesterol (mg/dL)
66 ± 15
67 ± 14
0.6 (−2.6–3.7)
65 ± 13
66 ± 13
0.4 (−2.2–3.1)
Triglycerides (mg/dL)
70 ± 33
86 ± 52
16.4 (−2.8–35.7)
79 ± 38
72 ± 46
−6.3 (−25.5–12.9)
Blood glucose (mg/dL)
84 ± 10
84 ± 9.4
0.1 (−5.1–5.3)
87 ± 5.6
84 ± 7.9*
−3.4 (−6.8–−0.1)
HbA1c (%, NGSP)
5.1 ± 0.2
5.0 ± 0.2*,a
−0.1 (−0.1–0.0)
5.1 ± 0.2
5.0 ± 0.2*
−0.1 (−0.1–0.0)
Uric acid (mg/dL)
5.2 ± 1.2
5.2 ± 1.1
0.1 (−0.2–0.3)
5.1 ± 1.1
5.1 ± 1.3
0.0 (−0.3–0.2)
Blood urea nitrogen (mg/dL)
14.3 ± 3.3
13.6 ± 2.7
−0.7 (−2.1–0.7)
13.6 ± 3.4
13.1 ± 3.2
−0.5 (−2.1–1.2)
Serum creatinine (mg/dL)
0.72 ± 0.16†
0.72 ± 0.17
0.00 (−0.02–0.02)
0.70 ± 0.15
0.71 ± 0.17
0.01 (−0.01–0.02)
Creatinine based-eGFR (mL/min/1.73 m2)
99.6 ± 16.4
99.6 ± 16.6
0.0 (−3.4–3.4)
102.0 ± 15.9
102.0 ± 19.0
0.1 (−2.9–3.0)
Serum cystatin C (mg/L)
0.83 ± 0.12†
0.79 ± 0.10**
−0.04 (−0.06–−0.02) †
0.79 ± 0.12
0.79 ± 0.12
−0.01 (−0.03–0.02)
Magnesium (mg/dL)
2.3 ± 0.1
2.4 ± 0.2*,†
0.1 (0.0–0.1)
2.3 ± 0.1
2.3 ± 0.2
0.0 (0.0–0.1)
Adiponectin (μg/mL)
11.0 ± 4.7
12.5 ± 5.3**
1.5 (0.6–2.4)
10.5 ± 4.6
11.7 ± 5.0
1.1 (−0.6–2.9)
Data are expressed as means ± SD. Changes in variables are expressed as means (95% CI). , End of consumption versus baseline (repeated ANOVA), , versus green tea (Paired t-test). a difference was examined by Wilcoxon rank test because normal distribution was not confirmed. BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure, HDL: high-density lipoprotein, eGFR: estimated glomerular filtration rate.
