Journal of Nutrition and Metabolism / 2011 / Article / Tab 5

Research Article

Protein and Amino Acid Supplementation Does Not Alter Proteolytic Gene Expression following Immobilization

Table 5

Fold changes from baseline for all genes of interest for placebo (PLA) and protein/amino acid (PAA) groups. All genes of interest showed significant increases over time ( ), but there was no difference noted between supplement groups. *Denotes a significant time effect.

GENEPLAPAA

Day14281428

Calpain1*9.40 ± 6.6712.21 ± 7.506.00 ± 3.1510.01 ± 5.26
Calpain2*4.06 ± 2.343.53 ± 1.794.71 ± 2.5111.12 ± 7.10
TNF-α*4.43 ± 1.826.17 ± 2.645.86 ± 2.554.81 ± 1.45
NF-κB*5.83± 2.239.93 ± 6.676.82 ± 3.145.98 ± 1.79
Ubiquitin*6.26 ± 3.515.86 ± 3.765.64 ± 2.5113.64 ± 6.67
C2*8.21 ± 4.599.37 ± 5.974.73 ± 2.0310.48 ± 3.92
C3*9.54 ± 5.6610.09 ± 5.407.32 ± 3.848.27 ± 3.53
Atrogin1*12.13 ± 8.4312.76 ± 8.955.48 ± 3.597.04 ± 3.07
MuRF1*5.19 ± 2.493.62 ± 1.988.33 ± 3.007.84 ± 2.58
E2*10.76 ± 6.3010.92 ± 6.466.17 ± 3.356.67 ± 2.43
E3*5.82 ± 3.0910.31 ± 6.3319.02 ± 9.6822.92 ± 14.27
Myostatin*8.98 ± 6.1816.74 ± 12.259.23 ± 5.4721.85 ± 15.33