Microarray Analyses of Genes Differentially Expressed by Diet (Black Beans and Soy Flour) during Azoxymethane-Induced Colon Carcinogenesis in Rats

Figure 4

Relative fold-changes in (a) Pla2g2a, (b) RatNP-3, (c) Col1a1, and (d) Fn1 detected with qRT-PCR. Results were normalized to the housekeeping gene β-Actin and are presented as mean fold-changes (LSM ± SEM) relative to the AIN(saline-injected) group. There were significant main effects for both diet and carcinogen for each gene presented (𝑃<0.05). *Denotes significant effect of diet compared to AIN controls; δ denotes significant effect of carcinogen treatment compared to saline controls (𝑃<0.05). Abbreviations: BB, black bean; SF, soy flour; Pla2g2a, phospholipase A2, group IIA; RatNP-3, rat neutrophil defensin 3; Col1a1, collagen, type I, alpha 1; Fn1, fibronectin 1.

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