Accelerated Growth Rate Induced by Neonatal High-Protein Milk Formula Is Not Supported by Increased Tissue Protein Synthesis in Low-Birth-Weight Piglets

Table 7

Plasma amino acid and urea concentrations measured in piglets fed NP, HP, and HPA diets at d7 and d28.

			d7					d28			Age effect
	NP	HP	HPA	P	SEM	NP	HP	HPA	P	SEM
Amino acids, μmol/L
Lysine	106.4^a	200.3^b	188.3^b	<0.05	26.23	198.2^a	336.9^b	306.9^b	<0.01	28.15	<0.001
Threonine	382.7^a	749.8^b	746.8^b	<0.1	132.26	470.9	583.5	578.6	ns	61.73	ns
Methionine	34.2^a	66.0^b	83.7^b	<0.05	11.31	91.1	78.2	72.7	ns	12.69	<0.05
Tryptophane	40.3^a	59.6^ab	71.6^b	<0.1	8.63	85.9	88.6	98.2	ns	8.98	<0.001
Leucine	205.1^a	299.1^b	310.1^b	<0.1	33.95	274.5	336.8	329.3	ns	23.64	<0.1
Valine	408.1^a	519.6^b	498.9^ab	<0.1	34.81	497.5	492.2	491.6	ns	25.91	ns
Isoleucine	153.3^a	226.1^b	225.9^b	<0.05	21.45	195.3	237.6	234.8	ns	18.04	ns
Phenylalanine	91.6	131.3	158.6	ns	22.15	97.9	118.2	119.6	ns	14.79	ns
Histidine	93.2	108.6	115.2	ns	18.46	143.2^a	104.7^b	128.2^ab	<0.1	11.55	ns
Arginine	118.4^a	172.6^b	227.2^b	<0.05	28.3	187.1	152.6	155.6	ns	30.50	ns
Alanine	649.7	695.5	660.2	ns	59.08	548.9	505.7	448.2	ns	44.11	<0.001
Asparagine	44.6	83.1	78.5	ns	16.80	77.6	72.9	72.7	ns	9.48	ns
Aspartic acid	42.1	71.7	69.2	ns	12.00	42.7	57.8	63.5	ns	9.03	ns
Citrulline	137.9	144.6	151.1	ns	14.78	214.4	142.5	167.7	ns	26.56	<0.1
Cystine	37.6	47.4	56.1	ns	8.63	34.3	21.3	20.9	ns	4.81	<0.001
Glutamine	424.7	531.5	559.8	ns	75.32	516.0	431.8	423.1	ns	37.67	ns
Glutamic acid	247.6	297.2	266.1	ns	36.29	332.5^a	249.1^b	228.1^b	<0.05	24.54	ns
Glycine	1250.7	1370.6	1444.1	ns	116.60	2182.7^a	1315.2^b	1291.9^b	<0.01	168.3	<0.05
Serine	245.2^a	311.4^b	336.1^b	<0.1	28.57	322.6^a	230.4^b	227.0^b	<0.05	25.49	<0.1
Ornithine	81.8	91.4	84.3	ns	6.12	166.7	152.9	173.5	ns	18.29	<0.001
Proline	712.3	860.7	816.2	ns	58.02	786.4	625.7	638.7	ns	91.43	<0.1
Taurine	206.7	269.1	341.6	ns	48.88	110.4^a	234.6^b	242.7^b	<0.01	24.89	<0.05
Tyrosine	125.5	220.4	240.6	ns	39.06	151.1	153.4	173.1	ns	19.55	ns
NH3, μmol/L	368.0	340.0	337.2	ns	38.66	379.9^a	486.8^b	476.9^b	<0.05	28.62	<0.001

Values are least square means and pooled SEM calculated in pigs slaughtered at d7 and d28, 𝑛=6/group. P (effect of formula) and age effect are presented. Differences were considered significant when 𝑃<0.05 but trends are presented when 0.1 < 𝑃<0.05. Means with a different superscript letter differ at 𝑃<0.05.