The Opposite Effects of High-Sucrose and High-Fat Diet on Fatty Acid Oxidation and Very Low Density Lipoprotein Secretion in Rat Model of Metabolic Syndrome
Table 1
Characteristics of experimental groups.
Prediet values
SD (post-diet)
HS (post-diet)
HF (post-diet)
HS versus SD
HF versus SD
Body weight (g)
281 ± 3
311 ± 4***
335 ± 15***
364 ± 10***
<0.05
<0.001
Epididymal fat (g)
—
2.8 ± 0.2
3.8 ± 0.3*
5.5 ± 0.5***
<0.05
<0.001
s-glucose (mmol/L)
Fasted
4.5 ± 0.2
4.6 ± 0.1
4.5 ± 0.05
5.4 ± 0.05*
N.S.
<0.05
Fed
6.2 ± 0.2
6 ± 0.1
11.4 ± 0.1***
7.6 ± 0.4*
<0.001
<0.05
s-insulin (pmol/L)
Fasted
126 ± 18
135 ± 21
155 ± 12
204 ± 20*
N.S.
<0.05
Fed
155 ± 20
158 ± 15
342 ± 29***
127 ± 18
<0.001
N.S.
s-TAG (mmol/L)
Fasted
1.3 ± 0.25
1.5 ± 0.3
4.9 ± 0.5***
1.4 ± 0.3
<0.001
N.S.
Fed
2 ± 0.4
2.4 ± 0.2
7.2 ± 0.4***
1.8 ± 0.2
<0.001
<0.05
s-FFA (mmol/L)
Fasted
0.65 ± 0.03
0.7 ± 0.05
1 ± 0.09*
0.6 ± 0.08
<0.05
N.S.
Fed
0.38 ± 0.02
0.4 ± 0.02
1.3 ± 0.1***
0.45 ± 0.07
<0.001
N.S.
s- hydroxyl butyrate (mol/L)
Fasted
1.2 ± 0.04
1.3 ± 0.05
2.2 ± 0.14**
3.8 ± 0.2***
<0.01
<0.001
Fed
0.02 ± 0.01
0.02 ± 0.01
0.03 ± 0.02
0.45 ± 0.05***
N.S.
<0.001
Data are given as mean ± SEM, . *, **, *** before versus after diet.
