The Opposite Effects of High-Sucrose and High-Fat Diet on Fatty Acid Oxidation and Very Low Density Lipoprotein Secretion in Rat Model of Metabolic Syndrome

Table 3

The incorporation of intracellular TAG-derived ¹⁴C palmitic acid into CO₂, TCA intermediates, secreted 𝛽-hydroxybutyrate, and secreted triacylglycerols from liver slices in vitro.

	SD		HS		HF
	Fasted	Fed	Fasted	Fed	Fasted	Fed
CO2 (released)	16 ± 1.2	11.9 ± 1	11 ± 1.5*	8.3 ± 0.3^†	15 ± 0.7	9.8 ± 0.8
TCA intermediates (intracellular)	55.3 ± 1.6	41 ± 3.4	46.6 ± 1.8**	25.7 ± 1.5^†††	54.2 ± 4.2	40.3 ± 1
𝛽-hydroxybutyrate (secreted)	269 ± 9	204 ± 8	380 ± 18**	178 ± 15	452 ± 22^###	480 ± 11^xxx
TAG (secreted)	581 ± 35	401 ± 44	713 ± 29**	825 ± 29^†††	314 ± 16^###	286 ± 35^xx

Data are expressed in nmol palmitic acid per g tissue and given as mean ± SEM 𝑛=6. *𝑃<0.05, **𝑃<0.01 HS fasted versus SD fasted; ^†𝑃<0.05, ^†††𝑃<0.001 HS fed versus SD fed; ^###𝑃<0.001 HF fasted versus SD fasted; ^xx𝑃<0.01, ^xxx𝑃<0.001 HF fed versus SD fed.