Research Article

Saturated Fatty Acid-Induced Cytotoxicity in Liver Cells Does Not Involve Phosphatase and Tensin Homologue Deleted on Chromosome 10

Figure 1

PTEN expression and effects of PTEN knockdown on triglyceride stores in liver cells. PTEN protein expression following 16 h of incubations with control media (LG) or fatty acids (oleate (O), linoleate (L), palmitate (P), or stearate (S)) at 250 μM (a) in H4IIE (left column) or HepG2 (right column) liver cells ( ). Effectiveness of SiRNA-mediated knockdown of PTEN in liver cells (b). Effects of SiRNA-mediated knockdown of PTEN on triglyceride stores in liver cells following 16 h of incubations with control media or fatty acids (c). *: significantly ( ) different from LG; +: significantly ( ) different from O250 and L250.
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