Table of Contents Author Guidelines Submit a Manuscript
Journal of Nutrition and Metabolism
Volume 2013 (2013), Article ID 653185, 7 pages
Clinical Study

A Single Consumption of High Amounts of the Brazil Nuts Improves Lipid Profile of Healthy Volunteers

1Department of Chemistry, Natural and Exact Sciences Centers, Federal University of Santa Maria (UFSM), 97105900 Santa Maria, RS, Brazil
2Department of Nutrition, Center Franciscan University (UNIFRA), Santa Maria, RS, Brazil
3Clinical Laboratory Analysis, University Hospital, Santa Maria, RS, Brazil
4Lutheran University of Brazil (ULBRA), Santa Maria, RS, Brazil
5Department of Technology and Food and Science, Federal University of Santa Maria (UFSM), Santa Maria, RS, Brazil

Received 20 April 2013; Revised 15 May 2013; Accepted 15 May 2013

Academic Editor: Cindy Davis

Copyright © 2013 Elisângela Colpo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. This study investigates the effects of Brazil nut ingestion on serum lipid profile in healthy volunteers. Methods. Ten healthy subjects were enrolled in the study. Each subject was tested 4 times in a randomized crossover in relation to the ingestion of different serving sizes of the Brazil nut: 0, 5, 20, or 50 g. At each treatment point, peripheral blood was drawn before and at 1, 3, 6, 9, 24, and 48 hours and 5 and 30 days. Blood samples were tested for total cholesterol, high- and low-density lipoprotein cholesterol (HDL-c and LDL-c, resp.), triglycerides, selenium, aspartate and alanine aminotransferases, albumin, total protein, alkaline phosphatase, gamma GT, urea, creatinine, and C-reactive protein. Results. A significant increase of the plasma selenium levels was observed at 6 hours within the groups receiving the nuts. Serum LDL-c was significantly lower, whereas HDL-c was significantly higher 9 hours after the ingestion of 20 or 50 g of nuts. The biochemical parameters of liver and kidney function were not modified by ingestion of nuts. Conclusions. This study shows that the ingestion of a single serving of Brazil nut can acutely improve the serum lipid profile of healthy volunteers.