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Journal of Nutrition and Metabolism
Volume 2014, Article ID 202759, 6 pages
Review Article

Nutrigenomics: Definitions and Advances of This New Science

1Universidade Anhembi Morumbi/Gerência de Nutrição Enteral e Parenteral, Rua Pedro Ivo 22, 01323-070 São Paulo, SP, Brazil
2BioLife Brasil Ltda, Distrito Agroindustrial de Formosa, Quadra 01, Lote 15, 73801-970 Formosa, GO, Brazil
3Gerência de Nutrição Enteral e Parenteral-GANEP, Rua Pedro Ivo 22, 01323-070 São Paulo, SP, Brazil

Received 19 November 2013; Revised 20 February 2014; Accepted 27 February 2014; Published 25 March 2014

Academic Editor: M. Meydani

Copyright © 2014 N. M. R. Sales et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The search for knowledge regarding healthy/adequate food has increased in the last decades among the world population, researchers, nutritionists, and health professionals. Since ancient times, humans have known that environment and food can interfere with an individual’s health condition, and have used food and plants as medicines. With the advance of science, especially after the conclusion of the Human Genome Project (HGP), scientists started questioning if the interaction between genes and food bioactive compounds could positively or negatively influence an individual’s health. In order to assess this interaction between genes and nutrients, the term “Nutrigenomics” was created. Hence, Nutrigenomics corresponds to the use of biochemistry, physiology, nutrition, genomics, proteomics, metabolomics, transcriptomics, and epigenomics to seek and explain the existing reciprocal interactions between genes and nutrients at a molecular level. The discovery of these interactions (gene-nutrient) will aid the prescription of customized diets according to each individual’s genotype. Thus, it will be possible to mitigate the symptoms of existing diseases or to prevent future illnesses, especially in the area of Nontransmissible Chronic Diseases (NTCDs), which are currently considered an important world public health problem.