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Journal of Nutrition and Metabolism
Volume 2014, Article ID 980547, 13 pages
Research Article

HO-1 Upregulation Attenuates Adipocyte Dysfunction, Obesity, and Isoprostane Levels in Mice Fed High Fructose Diets

1Department of Internal Medicine, Marshall University Joan C. Edwards School of Medicine, Huntington, WV 25701, USA
2Departments of Medicine and Pharmacology, New York Medical College, Valhalla, NY 10595, USA

Received 19 June 2014; Accepted 14 August 2014; Published 9 September 2014

Academic Editor: Stan Kubow

Copyright © 2014 Zeid Khitan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [12 citations]

The following is the list of published articles that have cited the current article.

  • Komal Sodhi, Nitin Puri, Gaia Favero, Sarah Stevens, Charles Meadows, Nader G. Abraham, Rita Rezzani, Hayden Ansinelli, Edward Lebovics, and Joseph I. Shapiro, “Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet,” Plos One, vol. 10, no. 6, 2015. View at Publisher · View at Google Scholar
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  • Silvia Rodrigo, Lourdes Rodríguez, Paola Otero, María I. Panadero, Antonia García, Coral Barbas, Núria Roglans, Sonia Ramos, Luis Goya, Juan C. Laguna, Juan J. Álvarez-Millán, and Carlos Bocos, “Fructose during pregnancy provokes fetal oxidative stress: The key role of the placental heme oxygenase-1,” Molecular Nutrition & Food Research, 2016. View at Publisher · View at Google Scholar
  • Jianan Zhang, Ou Wang, Yingjian Guo, Tuo Wang, Siyi Wang, Guopeng Li, Baoping Ji, and Qianchun Deng, “Effect of Increasing Doses of Linoleic and α-Linolenic Acids on High-Fructose and High-Fat Diet Induced Metabolic Syndrome in Rats,” Journal of Agricultural and Food Chemistry, 2016. View at Publisher · View at Google Scholar
  • Mehmet Bilgehan Pektas, Halit Bugra Koca, Gokhan Sadi, and Fatma Akar, “Dietary Fructose Activates Insulin Signaling and Inflammation in Adipose Tissue: Modulatory Role of Resveratrol,” BioMed Research International, vol. 2016, pp. 1–10, 2016. View at Publisher · View at Google Scholar
  • Komal Sodhi, Jordan Hilgefort, George Banks, Chelsea Gilliam, Sarah Stevens, Hayden A. Ansinelli, Morghan Getty, Nader G. Abraham, Joseph I. Shapiro, and Zeid Khitan, “Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity,” Stem Cells International, vol. 2016, pp. 1–11, 2016. View at Publisher · View at Google Scholar
  • Shailendra P. Singh, Lars Bellner, Luca Vanella, Jian Cao, John R. Falck, Attallah Kappas, and Nader G. Abraham, “ Downregulation of PGC-1 α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice ,” Journal of Nutrition and Metabolism, vol. 2016, pp. 1–15, 2016. View at Publisher · View at Google Scholar
  • Tamara Merz, Tatjana Stenzel, Benedikt Nußbaum, Martin Wepler, Csaba Szabo, Rui Wang, Peter Radermacher, and Oscar McCook, “Cardiovascular disease and resuscitated septic shock lead to the downregulation of the H2S-producing enzyme cystathionine-γ-lyase in the porcine coronary artery,” Intensive Care Medicine Experimental, vol. 5, no. 1, 2017. View at Publisher · View at Google Scholar
  • Zheng Wang, Sun-O Ka, Youngyi Lee, Byung-Hyun Park, and Eun Ju Bae, “Butein induction of HO-1 by p38 MAPK/Nrf2 pathway in adipocytes attenuates high-fat diet induced adipose hypertrophy in mice,” European Journal of Pharmacology, 2017. View at Publisher · View at Google Scholar
  • Nitin Puri, Yevgeniy Arefiev, Robert Chao, David Sacerdoti, Hibba Chaudry, Alexandra Nichols, Krithika Srikathanan, Athar Nawab, Dana Sharma, Vishal Hari Lakhani, Rebecca Klug, Komal Sodhi, and Stephen J. Peterson, “Heme Oxygenase Induction Suppresses Hepatic Hepcidin and Rescues Ferroportin and Ferritin Expression in Obese Mice,” Journal of Nutrition and Metabolism, vol. 2017, pp. 1–11, 2017. View at Publisher · View at Google Scholar
  • Xiaohua Liu, Caixia Ji, Li Xu, TingTing Yu, Chaoqun Dong, and Jinyong Luo, “Hmox1 promotes osteogenic differentiation at the expense of reduced adipogenic differentiation induced by BMP9 in C3H10T1/2 cells,” Journal of Cellular Biochemistry, 2018. View at Publisher · View at Google Scholar